Transfer of dorsoventral and terminal Information from the ovary to the embryo by a common group of eggshell proteins in drosophila

摘要: The Drosophila eggshell is an extracellular matrix that confers protection to the egg and also plays a role in transferring positional information from ovary pattern embryo. Among constituents of eggshell, Nasrat, Polehole, Closca form group proteins related by sequence, secreted oocyte, mutually required for their incorporation into eggshell. Besides integrity, are embryonic terminal patterning anchoring or stabilizing Torso-like at Here, we show they dorsoventral patterning, thereby unveiling systems, hitherto considered independent, share common step. Furthermore, proper Nudel activity, protease acting both thus providing means account Closca. We propose Nasrat/Polehole/Closca complex acts as multifunctional hub anchor various synthesized oogenesis, ensuring spatial temporal restricted function.