Compositions and methods for the prophylaxis and treatment of aphthous ulcers and herpes simplex lesions

作者: Win L. Chiou , Linda L. Chiou

DOI:

关键词: PharmacologyImmunologyAntimicrobialMucosal UlcerAnalgesicMedicineEffective treatment

摘要: Disclosed is a topical method for providing adequate analgesic, anti-inflammatory, antimicrobial and tissue-regenerating activities the hitherto most effective prophylaxis treatment of aphtous ulcers herpes simplex lesions burns other oral mucosal comprising topically administering to affected tissue an amount composition comprised one or more safe efficacious polyvalent metal compounds such as magnesium sulfate, preferably with anti-inflammatory compounds, novel ultra-low-strength hydrocortisone (acetate), that potentiate compounds. Both ionic neutral moieties metals are pharmacologically active; water-soluble water-insoluble both therapeutically effective.

参考文章(11)
Phillip Campbell, Lesion and ulcer medication ,(2001)
Pradeep K. Dhal, Thomas X. Neenan, W. Harry Mandeville, Richard J. Fitzpatrick, Philip J. Goddard, Jeffrey D. Klinger, Bismuth compounds for the treatment and prevention of mucositis ,(2001)
Marianne Flowers, Basilio Tavares, Treatment of topical infections ,(1991)
David Cullis-Hill, Method for topical treatment of herpes infections Official Gazette of the United States Patent and Trademark Office Patents. ,vol. 1186, pp. 434- ,(1995)
Michael P. Romanowsky, David W. Pehrson, Topical preparation for treatment of aphthous ulcers and other lesions ,(1990)
Kenneth T. Richardson, Don C. Pearson, Unit dosage forms for the treatment of herpes simplex ,(2001)
H. L. Waldum, S. A. Nordbø, L. S. Bevanger, A Bismuth Salt Inhibits Herpes Simplex Virus Microbial Ecology in Health and Disease. ,vol. 10, pp. 13- 15 ,(1998) , 10.3402/MEHD.V10I1.7820
Philip Domenico, Metal/Thiol biocides ,(1998)