Dapsone therapy of cicatricial pemphigoid.

摘要: Dapsone and the related sulfapyridine have been valuable therapeutic agents in many inflammatory disease states although exact mechanism of action remains unclear. In patients with mild CP or localized (gingival ocular) variants, dapsone has shown to be a relatively safe, first drug choice therapy before commencing treatment systemic corticosteroids and/or immunosuppressive agents. extensive, severe, rapidly progressive CP, initial dose 1 2 mg/kg/d prednisone plus such as azathioprine cyclophosphamide 3 are recommended.