New trends in the production of pharmaceutical granules: batch versus continuous processing.

作者: Hans Leuenberger

DOI: 10.1016/S0939-6411(01)00199-0

关键词: Pharmaceutical industryPharmaceutical technologyProcess engineeringSCALE-UPGranulationQuality assuranceBatch productionGranule (cell biology)Computer scienceProduction line

摘要: … However, it has to be noticed that a technology and knowledge transfer, … device such as a marumerizer with a fixed capacity, the manufacture of pellets ends up as a batch-type process. …

参考文章(7)
H Leuenberger, Granulation, new techniques. Pharmaceutica Acta Helvetiae. ,vol. 57, pp. 72- 82 ,(1982)
Wolfgang Pietsch, Size enlargement by agglomeration ,(1991)
S Inghelbrecht, The roller compaction of different types of lactose. International Journal of Pharmaceutics. ,vol. 166, pp. 135- 144 ,(1998) , 10.1016/S0378-5173(98)00022-2
P. KLEINEBUDDE, A. J. SØLVBERG, H. LINDNER, The power-consumption-controlled extruder: a tool for pellet production. Journal of Pharmacy and Pharmacology. ,vol. 46, pp. 542- 546 ,(2011) , 10.1111/J.2042-7158.1994.TB03853.X
Chris Vervaet, Lieven Baert, Jean Paul Remon, Extrusion-spheronisation A literature review International Journal of Pharmaceutics. ,vol. 116, pp. 131- 146 ,(1995) , 10.1016/0378-5173(94)00311-R
C Lustig-Gustafsson, H Kaur Johal, F Podczeck, J.M Newton, The influence of water content and drug solubility on the formulation of pellets by extrusion and spheronisation. European Journal of Pharmaceutical Sciences. ,vol. 8, pp. 147- 152 ,(1999) , 10.1016/S0928-0987(99)00004-4