Antitumor carboplatin is more toxic in tumor cells when photoactivated: enhanced DNA binding.
作者： Jarmila Mlcouskova , Jana Stepankova , Viktor Brabec
DOI: 10.1007/S00775-012-0906-Z
关键词: Cancer cell 、 Cancer 、 Ligand (biochemistry) 、 Carboplatin 、 Toxicity 、 Chemistry 、 Cancer research 、 Cytotoxicity 、 Photochemistry 、 Cisplatin 、 Cytotoxic T cell
摘要: … in the present work in a cell-free medium indicated that the modification reaction resulting in the irreversible coordination of photoactivated carboplatin to DNA was markedly faster than …
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