作者: Divya Adhia , Berthold Langguth , Dirk De Ridder
关键词: Cortex (anatomy) 、 Neuroscience 、 Neuromodulation (medicine) 、 Brain stimulation 、 Neurostimulation 、 Stimulation 、 Tinnitus 、 Deep brain stimulation 、 Temporal cortex 、 Medicine
摘要: The pathophysiological mechanisms that underlie the generation and maintenance of tinnitus are being unraveled progressively. Based on this knowledge, a large variety different neuromodulatory interventions have been developed still designed, adapting to progressive mechanistic insights in pathophysiology tinnitus. rTMS targeting temporal, temporoparietal, frontal cortex has mainstay non-invasive neuromodulation. Yet, evidence is unclear, therefore systematic meta-analyses needed for drawing conclusions effectiveness chronic Different forms transcranial electrical stimulation (tDCS, tACS, tRNS), applied over temporal cortex, investigated patients, also without robust universal efficacy. Cortex deep brain with implanted electrodes shown benefit, yet there insufficient data support their routine clinical use. Recently, bimodal approaches revealed promising results it appears sensory modalities temporally combined manners may be more than single target approaches.While most seem promising, further research required help translating scientific outcomes into practice.