Transcatheter aortic valve-in-valve implantation: clinical outcome as defined by VARC-2 and postprocedural valve dysfunction according to the primary mode of bioprosthesis failure.

摘要: OBJECTIVES The objectives of this study were to investigate: (1) the clinical outcome transcatheter aortic valve-in-valve (VIV) implantation according Valve Academic Research Consortium (VARC)-2 criteria; and (2) determine whether postprocedural transvalvular gradients differ in patients with bioprosthesis regurgitation or stenosis as primary mode failure. BACKGROUND Transcatheter VIV has become a feasible option for selected high-risk failed surgical bioprostheses. METHODS was performed 14 individuals at University Zurich College London. RESULTS prosthesis successfully implanted 13 (93%). In 1 patient, second valve needed be due malpositioning. Thirty-day all-cause mortality 7% (1/14). Prosthetic dysfunction VARC-2 30 days observed 7/14 (50%) an increased gradient >20 mm Hg. Preprocedural transaortic correlated significantly (r=0.91; P<.001). At 30-day follow-up, higher failure compared those (36 ± 6 Hg vs 16 4 Hg; P=.01). None exhibited prosthetic more than mild degree. CONCLUSION feasibility safety bioprostheses is demonstrated. A after