Fabrication of multi-stimuli responsive supramolecular hydrogels based on host–guest inclusion complexation of a tadpole-shaped cyclodextrin derivative with the azobenzene dimer
作者： Xing Wang , Juan Wang , Yanyu Yang , Fei Yang , Decheng Wu
DOI: 10.1039/C7PY00698E
关键词: Drug delivery 、 Supramolecular chemistry 、 Nanotechnology 、 Polymer 、 Dimer 、 Biocompatibility 、 Supramolecular polymers 、 Polymer chemistry 、 Azobenzene 、 Chemistry 、 Self-healing hydrogels
摘要: Motivated by the demand for high-performance soft materials applications in catalysis, drug delivery and biomedical materials, development of smart hydrogels that possess both biocompatibility stimulus responsiveness has been highly desirable. Here, we demonstrated a facile method to construct multi-responsive supramolecular hydrogel formation host–guest complexes between tadpole-shaped PEG-POSS-(CD)7 polymer Azo-SS-Azo dimer. Incorporation rigid POSS units furnished cross-linked networks with high mechanical strength. The reversible gel–sol phase transition could be induced temperature, light redox while Azo derivatives induce quick transition. These novel also possessed favorable self-healing ability better biocompatibility, which endowed potential practical real-life will beneficial further more intelligent desired functionalities.
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