作者: Emaad M Abdel-Rahman , Tarek Alhamad , W Brian Reeves , Alaa S Awad
DOI: 10.4172/2161-0959.1000124
关键词: Medicine 、 Proteinuria 、 Internal medicine 、 Glycemic 、 Diabetes mellitus 、 Angiotensin-converting enzyme 、 Albuminuria 、 Diabetic nephropathy 、 Disease 、 Population 、 Bioinformatics
摘要: The incidence and prevalence of End-Stage Renal Disease (ESRD) secondary to Diabetic Nephropathy (DN) have been progressively increasing, reaching pandemic proportions over the past 20 years. Diabetes mellitus is responsible for more than 40% all cases ESRD in United States. Despite that, treatment DN still suboptimal. Both elderly diabetic populations are among fastest growing categories. While several guidelines available management general population, patients unique characteristics that may require adaptation therapeutic used population. Current therapy directed at delaying progression includes optimal glycemic blood pressure control, proteinuria/albuminuria reduction, interruption renin-angiotensin-aldosterone system through use angiotensin converting enzyme inhibitors type-1 receptor blockers, along with dietary modification cholesterol lowering agents. This review highlights standard approaches manage progressive elderly.