A Combination Chemotherapy Protocol (VELCAP‐L) for Dogs with Lymphoma

摘要: Ninety-eight dogs with lymphoma treated a 5-drug combination chemotherapy regimen (vincristine, L-asparaginase, cyclophosphamide, doxorubicin, prednisone [VELCAP-L]) were evaluated for pretreatment characteristics predictive response and remission duration. The complete rate was 69%, median duration of 55 weeks. Dogs advanced stage disease, constitutional signs, that older, dyspneic less likely to achieve remission. Once in remission, small without thrombocytopenia have longer Toxicoses frequent, but rarely fatal, no predictitive factors found dog developing toxicoses. VELCAP-L is an effective treatment I-III lymphoma, particularly young, animals.