作者: Michael G Zywiel , D Alex Stroh , Seung Yong Lee , Peter M Bonutti , Michael A Mont
DOI: 10.2106/JBJS.J.01473
关键词: Opioid 、 Referral 、 Degenerative disease 、 Perioperative 、 Evidence-based medicine 、 Medicine 、 Surgery 、 Anesthesia 、 Hyperalgesia 、 Rehabilitation 、 Orthopedic surgery
摘要: Background: Chronic use of opioid medications may lead to dependence or hyperalgesia, both which might adversely affect perioperative and postoperative pain management, rehabilitation, clinical outcomes after total knee arthroplasty. The purpose this study was evaluate patients who underwent arthroplasty following six more weeks chronic for control compare them with a matched group did not opioids preoperatively. Methods: Forty-nine knees in had mean age fifty-six years (range, thirty-seven seventy-eight years) regularly used prior were compared them. Length hospitalization, aseptic complications requiring reoperation, requirement specialized assessed groups. Results: Knee Society scores significantly lower the at time final follow-up (mean, three years; range, two seven years); 79 points 45 100 points) as 92 59 non-opioid group. A higher prevalence seen group, five arthroscopic evaluations eight revisions persistent stiffness and/or pain, none Ten referred outpatient one patient group. Conclusions: Patients chronically be substantially greater risk painful prolonged recoveries. Alternative earlier referral an orthopaedic surgeon habitual should considered degenerative disease knee. Level Evidence: Therapeutic Level III. See Instructions Authors complete description levels evidence.