Phylogenetic analysis reveals extensive evolution of avian paramyxovirus type 1 strains of pigeons (Columba livia) and suggests multiple species transmission*1

摘要: Partial sequence and residue substitution analyses of the fusion protein gene were performed for 68 strains avian paramyxovirus type 1 pigeons (PPMV-1), an antigenic variant Newcastle disease virus (NDV) chickens, derived from 16 countries between 1978 2002. The majority isolates clustered into a single genetic lineage, termed VIb/1, within genotype VI NDV whereas small number that originated in Croatia after 1995, grouped highly diverged VIb/2, indicating separate host-switching event VIb/1 strains. Four distinct subgroups lineage Iraqi (IQ), early European (EU/ea), North American (NA) recent (EU/re) have emerged circulated past decades. Subgroup EU/ea NA responsible main streams infection 1980s, while EU/re viruses infections 1990s. degree diversity phase epizootic suggested prolonged period pigeon-type prior to emergence 1980s. Shared character analysis showed close relationship Sudanese mid-1970, suggesting PPMV-1 could be African origin.