Treatment of eosinophilic esophagitis: drugs, diet, or dilation?

摘要: A number of recent studies have demonstrated that a variety treatments effectively improve symptoms and histology in the majority patients with eosinophilic esophagitis. Therapeutic options include pharmacologic treatments, such as oral topical corticosteroids leukotriene-receptor antagonists. In children, high response rates to dietary modification elimination suggest certain foods may serve environmental triggers for infiltration. Because many adults present strictures, endoscopic esophageal dilation is another management modality. Despite these treatment options, several controversies exist recommended strategy. Whether goal therapy resolution symptoms, tissue eosinophilia, or both remains uncertain owing paucity data on natural history condition. Furthermore, important differences clinical presentations esophagitis children point toward possible need different approaches two patient populations.