Glycogen synthase kinase 3 in the world of cell migration.

作者: Tong Sun , Marbelys Rodriguez , Leung Kim

DOI: 10.1111/J.1440-169X.2009.01141.X

关键词: Cell functionCell polarityBiologyCell biologyActin cytoskeletonGSK-3Cell migrationMicrotubuleCell adhesionKinase

摘要: Glycogen synthase kinase 3 (GSK3) is one of the few master switch kinases that regulate many aspects cell functions. Recent studies on polarization and migration have shown GSK3 also essential for proper regulation these processes. influences as regulators spatiotemporally controlled dynamics actin cytoskeleton, microtubules, cell-to-matrix adhesions. In this mini-review, effects three will be discussed.

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