作者: Brandon G Busbee , Melissa M Brown , Gary C Brown , Sanjay Sharma
DOI: 10.1016/S0161-6420(03)00796-6
关键词: Outcomes research 、 Pediatrics 、 Cataract surgery 、 Prospective cohort study 、 Medicine 、 Pseudophakia 、 Eye disease 、 Quality-adjusted life year 、 Visual acuity 、 Cost–utility analysis 、 Surgery
摘要: Abstract Objective To perform a reference case cost-utility analysis of second-eye cataract surgery by using the current literature on outcomes and complications. Design Computer-based econometric modeling. Methods Visual acuity data patients treated observed over 4-month postoperative period were obtained from U.S. National Cataract Patient Outcomes Research Team report. The results this prospective study combined with those other studies that investigated complication rates to complete cohort outcomes. These synthesized incorporated time trade-off utility values, which accounted for prior successful in fellow eye. Cost-utility determinations made decision analysis, present value modeling was used account money health state consequences. Main outcome measures number quality-adjusted life-years (QALYs) gained calculated group undergoing surgery, assuming vision second eye equivalent first after (20/27). This divided into cost procedure find year 2001 nominal dollars spent per QALY gained. Results Second-eye as compared unilateral pseudophakia, resulted mean gain 1.31 undiscounted QALYs patient treated. A 3% annual discount rate, dependent duration benefit, used, yielding 0.92 discounted 12-year life expectancy. treatment each totaled $2509. (benefit) $2727 procedure. Sensitivity varying costs values revealed range $2045 $3649 Conclusions is an extremely cost-effective when interventions across medical specialties. cost-effectiveness diminishes only slightly $2023 first-eye surgery. suggests good one visual loss derive substantial benefit extraction.