Electrical storm in patients with transvenous implantable cardioverter-defibrillators: Incidence, management and prognostic implications

摘要: Abstract Objectives. The purpose of this study was to determine the precise incidence, therapeutic options and prognostic implications electrical storm in patients with transvenous implantable cardioverter-defibrillator (ICD) systems. Background. Approximately 50% 70% treated an ICD receive appropriate device-based therapy within first 2 years. Most arrhythmic events require only one firing for termination. However, some multiple shocks during a short period time, condition referred as “arrhythmic or storm.” Methods. This prospectively designed observational comprised 136 recipients ICDs who were followed 403 ± 242 days. Electrical defined ventricular tachycardia fibrillation resulting device intervention ≥3 times single 24-h period. Results. During follow-up, 57/136 (42%) received therapy. occurred 14/136 (10%) at average 133 135 days after implantation. mean number episodes constituting 17 (range: 3 50; median 8) per patient. In 12 patients, required hospital admission. arrhythmia cluster could be terminated by combined β-blockers intravenous amiodarone whereas class I antiarrhythmic drugs occasionally successful. cumulative probability survival estimated Kaplan-Meier method showed that episode did not have worse outcome compared those without such event. Conclusions. represents frequent event modern ICDs. It occurs most commonly late implantation can managed amiodarone. does independently confer increased mortality.