HDACs link the DNA damage response, processing of double-strand breaks and autophagy
作者： Thomas Robert , Fabio Vanoli , Irene Chiolo , Ghadeer Shubassi , Kara A. Bernstein
DOI: 10.1038/NATURE09803
关键词: CHEK1 、 Biochemistry 、 DNA damage 、 DNA repair 、 Cell biology 、 Autophagy 、 Biology 、 Chromatin 、 G2-M DNA damage checkpoint 、 Histone deacetylase 、 DNA repair protein XRCC4
摘要: … However, it is unclear how acetylation modulates the DNA … protein Sae2 (human CtIP) is acetylated and degraded after HDAC … pathway, DSB repair, protein acetylation and autophagy. …
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