Certain Chemorheologic Considerations Regarding the Blood Vascular Interface with Particular Reference to Coronary Artery Disease

作者: DONALD L. FRY

DOI: 10.1161/01.CIR.40.5S4.IV-38

关键词: Compression (physics)Arterial treeInternal medicineStress (mechanics)Permeability (electromagnetism)PopulationMedicineTension (geology)Coronary artery diseasePathologyCardiologyStrain energy density function

摘要: The locations of coronary atheroma in a hyperlipemic dog are shown to occur at points the arterial tree where one would expect most intense exposure physical stress. Studies presented that were designed quantify certain aspects histological and physicochemical response intima variety acutely imposed mechanical stresses. These results indicate endothelial-cell population has an acute yield stress shear about 400 dynes/cm2; excess this is associated with cytological chemical changes, suggesting processes occurring, such as "yielding," "melting," "dissolving," "imbibition," "permeation" interfacial tissues; even absence permeability interface for albumin increased by increasing acting on whether shear, compression, or tension. relations these events tissue rheology, strain energy density of...

参考文章(0)