HIV surveillance by testing saliva.

摘要: Saliva specimens were tested for HIV antibody (anti-HIV) by an immunoglobulin G (IgG) capture radioimmunoassay (GACRIA) and three sensitive commercial assays. In tests on 460 seronegative subjects 196 seropositive GACRIA was 99.8% specific 100% sensitive. The Wellcome monoclonal Abbott recombinant DNA enzyme-linked immunosorbent assays (ELISAs) also highly (99.8%, 100%) but they less (90.9%, 82.0%). Fujirebio particle agglutination assay (97.8%) its specificity poor (84.1%). testing saliva from populations with anti-HIV prevalence greater than 0.5%, sampling alone could provide a good estimate of the true prevalence. For prevalences 0.5% estimates only be obtained if positive reactions confirmed another independent salivary assay. Salivary anti is convenient potentially accurate epidemiological tool.