VASOPRESSIN AND PROSTAGLANDINS IN PREMENSTRUAL PAIN AND PRIMARY DYSMENORRHEA

作者: P. Strömberg , M. Åkerlund , M. L. Forsling , E. Granström , H. Kindahl

DOI: 10.3109/00016348409156715

关键词: HormoneMenstrual painUterine stimulantsHuman uterusProstaglandinEndocrinologyPlasma concentrationInternal medicineMenstruationMedicineVasopressin

摘要: Both vasopressin and PGF2alpha are effective uterine stimulants in the non-pregnant human uterus, especially around onset of menstruation. In order to clarify relationship these hormones menstrual pain, plasma concentrations two prostaglandin metabolites (lS-keto-B.H-dihydro-PGF2alpha 11-ketotetranor PGF metabolites) were measured serial blood samples taken premenstrually during Five women with premenstrual pain gave 7-9 at intervals 30 minutes on day preceding From 5 severe primary dysmenorrhea a corresponding series first Two groups no symptoms served as controls, either or significantly higher than control group. Even markedly fluctuating levels found ...

参考文章(11)
V. Lundström, K. Green, Endogenous levels of prostaglandin F2α and its main metabolites in plasma and endometrium of normal and dysmenorrheic women American Journal of Obstetrics and Gynecology. ,vol. 130, pp. 640- 646 ,(1978) , 10.1016/0002-9378(78)90320-4
Elisabeth Granström, Hans Kindahl, Marja-Liisa Swahn, Profiles of prostaglandin metabolites in the human circulation Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. ,vol. 713, pp. 46- 60 ,(1982) , 10.1016/0005-2760(82)90165-5
M. Akerlund, K.-E. Andersson, I. Ingemarsson, EFFECTS OF TERBUTALINE ON MYOMETRIAL ACTIVITY, UTERINE BLOOD FLOW, AND LOWER ABDOMINAL PAIN IN WOMEN WITH PRIMARY DYSMENORRHOEA British Journal of Obstetrics and Gynaecology. ,vol. 83, pp. 673- 678 ,(1976) , 10.1111/J.1471-0528.1976.TB00911.X
Involvement of prostaglandins in vasopressin stimulation of the human uterus British Journal of Obstetrics and Gynaecology. ,vol. 90, pp. 332- 337 ,(1983) , 10.1111/J.1471-0528.1983.TB08919.X
Mats Åkerlund, PATHOPHYSIOLOGY OF DYSMENORRHEA Acta Obstetricia et Gynecologica Scandinavica. ,vol. 58, pp. 27- 32 ,(1979) , 10.3109/00016347909157786
RONALD W. SKOWSKY, LUCINDA SWAN, PHILIP SMITH, Effects of sex steroid hormones on arginine vasopressin in intact and castrated male and female rats. Endocrinology. ,vol. 104, pp. 105- 108 ,(1979) , 10.1210/ENDO-104-1-105
P. MELIN, H. VILHARDT, G. LINDEBERG, L.-E. LARSSON, M. ÅKERLUND, INHIBITORY EFFECT OF O-ALKYLATED ANALOGUES OF OXYTOCIN AND VASOPRESSIN ON HUMAN AND RAT MYOMETRIAL ACTIVITY Journal of Endocrinology. ,vol. 88, pp. 173- 180 ,(1981) , 10.1677/JOE.0.0880173
Mary L. Forsling, P. Strömberg, M. Åkerlund, Effect of ovarian steroids on vasopressin secretion. Journal of Endocrinology. ,vol. 95, pp. 147- 151 ,(1982) , 10.1677/JOE.0.0950147
Olof Widholm, Dysmenorrhea during adolescence. Acta Obstetricia et Gynecologica Scandinavica. ,vol. 58, pp. 61- 66 ,(1979) , 10.3109/00016347909157792