PIPERAZINYL-IMIDAZO(1,2-A)PYRAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

作者: Lumma William C

DOI:

关键词: Medicinal chemistryOrganic chemistryAlkoxy groupPiperazinePyrazineChemistryAlkylHalogen

摘要: Abstract of EP0013914Compounds formula wherein, R1 and R2 are hydrogen, alkyl, cycloalkyl, alkylthio, halo, -CF3, CF3S-, phenyl optionally substituted by halogen, alkyl or alkoxy, -CH2NR4R5 -SO2NR6R7 joined together form -(CH2)n-, n= 3 4, R3 is cycloalkylalkyl, cycloalkyl alkanoyl Y -CN, -CF3), alkoxy -COOH, prepared reaction between halo-imidazo (1,2-a) pyrazines with piperazine derivatives, found to be active anorexic, antidepressant, antihypertensive. analgesic, antiarrhythmic, and/or antismoking agents.

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