作者: Lumma William C
DOI:
关键词: Medicinal chemistry 、 Organic chemistry 、 Alkoxy group 、 Piperazine 、 Pyrazine 、 Chemistry 、 Alkyl 、 Halogen
摘要: Abstract of EP0013914Compounds formula wherein, R1 and R2 are hydrogen, alkyl, cycloalkyl, alkylthio, halo, -CF3, CF3S-, phenyl optionally substituted by halogen, alkyl or alkoxy, -CH2NR4R5 -SO2NR6R7 joined together form -(CH2)n-, n= 3 4, R3 is cycloalkylalkyl, cycloalkyl alkanoyl Y -CN, -CF3), alkoxy -COOH, prepared reaction between halo-imidazo (1,2-a) pyrazines with piperazine derivatives, found to be active anorexic, antidepressant, antihypertensive. analgesic, antiarrhythmic, and/or antismoking agents.