Advances in Dissolution Technology: Design, Pros and Cons

作者: C. D. Lathia , U. V. Banakar

DOI: 10.3109/03639048609048021

关键词: Biochemical engineeringNanotechnologyDesign technologyDissolutionComputer scienceIn vitro dissolution

摘要: AbstractTo date dissolution tests are considered to be the most reliable predictors of bioavailability drugs. Dissolution critical and difficult carry out properly. A review different apparatii currently in use or employed past is present along with advantages disadvantages offered by each. Criteria as design, operation, sensitivity, etc. an vitro system outlined which would assist fabrication a more efficient apparatus. If one obtain meaningful results, care attention must given those aspects that have been identified crucial. To no universal dissolutiuon test has yet devised every instance gives same rank order for vivo availability formulation batches.

参考文章(39)
A. G. MITCHELL, DOROTHY J. SAVILLE, The dissolution of aspirin and aspirin tablets Journal of Pharmacy and Pharmacology. ,vol. 19, pp. 729- 734 ,(2011) , 10.1111/J.2042-7158.1967.TB08024.X
Louis C. Schroeter, John G. Wagner, Automated Dissolution Rate Studies of Capsules and Tablets Journal of Pharmaceutical Sciences. ,vol. 51, pp. 957- 962 ,(1962) , 10.1002/JPS.2600511012
K. Marshall, D. B. Brook, A simplified dissolution rate apparatus. Journal of Pharmacy and Pharmacology. ,vol. 21, pp. 790- 792 ,(2011) , 10.1111/J.2042-7158.1969.TB08176.X
Gerhard Levy, William Tanski, Precision Apparatus for Dissolution Rate Determinations Journal of Pharmaceutical Sciences. ,vol. 53, pp. 679- 679 ,(1964) , 10.1002/JPS.2600530624
F. Langenbucher, In Vitro Assessment of Dissolution Kinetics: Description and Evaluation of a Column-type Method Journal of Pharmaceutical Sciences. ,vol. 58, pp. 1265- 1272 ,(1969) , 10.1002/JPS.2600581025
W.I. Higuchi, E.N. Hiestand, Dissolution Rates of Finely Divided Drug Powders I Journal of Pharmaceutical Sciences. ,vol. 52, pp. 67- 71 ,(1963) , 10.1002/JPS.2600520114
Herbert Lapidus, Nicholas G. Lordi, Some Factors Affecting the Release of a Water-Soluble Drug from a Compressed Hydrophilic Matrix Journal of Pharmaceutical Sciences. ,vol. 55, pp. 840- 843 ,(1966) , 10.1002/JPS.2600550818