Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion

摘要: The present invention discloses certain chirally correct polyene cyclodextrin acetals and hemiacetals (formula I) that are effective in providing skin clarification, which is useful for the treatment of acne, disfigurements darkening resulting from acne; cancer, diabetes, radiation treatments, chemotherapy, sun-burn; mitochondrial DNA dysfunction; age spots; loss cellular antioxidants; changes associated with aging including collagen loss, pliability, suppleness, wrinkles fine lines, oxidation, damage radiation, free radicals, UV; dry skin; xerosis; ichthyosis; dandruff; brownish keratoses; melasma; lentigines; liver pigmentation pigmented spots, dark circles under eyes, darkened skin, blemishes; oily warts; eczema; pruritic psoriasis; inflammatory dermatoses; topical inflammation; disturbed keratinization; scalp dryness, combinations thereof;