The UCLA population studies of CORD: X. A cohort study of changes in respiratory function associated with chronic exposure to SOx, NOx, and hydrocarbons.
作者： R Detels , D P Tashkin , J W Sayre , S N Rokaw , F J Massey
关键词: Population 、 Toxicology 、 Medicine 、 Cord 、 Cohort study 、 Spirometry 、 Physiology 、 Respiratory system 、 Respiratory function 、 Statistical significance 、 Toxicity
摘要: Two never-smoking cohorts in Southern California, one Lancaster (N = 2340) exposed only to moderate levels of oxidants and the other Long Beach 1326) high SOx, NO2, hydrocarbons particulates completed spirometry single-breath nitrogen test five six years apart. Forty-seven percent 45 participants were retested. Mean results at baseline for those tested not retested similar. Loss follow-up was primarily due moving (39 47 percent). Every difference consequence indicated greater deterioration lung function Beach. The level significance greatest, even youngest age groups, delta N2(750-1250), suggesting that earliest site impairment may occur small airways. Greater spirometric parameters observed every group females above seven males 15 age, chronic exposure pollutant mix occurring ultimately adversely affects large airways as well
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