Angiographic findings and clinical correlates in patients with cardiogenic shock complicating acute myocardial infarction: a report from the SHOCK Trial Registry

作者: S Chiu Wong , Timothy Sanborn , Lynn A Sleeper , John G Webb , Robert Pilchik

DOI: 10.1016/S0735-1097(00)00873-1

关键词: Heart diseaseTIMICardiogenic shockMyocardial infarction complicationsMyocardial infarctionAngiographyInternal medicineRight coronary arteryCardiologyMedicineCoronary circulation

摘要: OBJECTIVES We sought to delineate the angiographic findings, clinical correlates and in-hospital outcomes in patients with cardiogenic shock (CS) complicating acute myocardial infarction. BACKGROUND Patients CS infarction carry a grave prognosis. Detailed findings large, prospectively identified cohort of are currently lacking. METHODS compared characteristics, 717 selected undergo angiography 442 not selected, overall by etiology: left or right ventricular failure versus mechanical complications. RESULTS who underwent had lower baseline risk better hemodynamic profile than those did not. Overall, 15.5% significant main lesions on angiography, 53.4% three-vessel disease, higher rates both for failure, Among significantly mortality complications (45.2% vs. 57.0%; p = 0.021). Importantly, also correlated disease severity: 35.0% no single-vessel 50.8% disease. Furthermore, was associated culprit lesion location (78.6% lesion, 69.7% saphenous vein graft lesions, 42.4% circumflex 42.3% anterior descending 37.4% coronary artery lesions), Thrombolysis In Myocardial Infarction (TIMI) flow grade (46.5% TIMI 0/1, 49.4% 2 26% 3). CONCLUSIONS study SHOCK Trial Registry more benign cardiac profile, favorable whom angiograms were obtained. caused severe atherosclerosis, different distribution vessel involvement but mortality, Overall survival extent obstructions, grade.

参考文章(40)
Stephen Scheidt, Robert Ascheim, Thomas Killip, Shock after acute myocardial infarction The American Journal of Cardiology. ,vol. 26, pp. 556- 564 ,(1970) , 10.1016/0002-9149(70)90407-8
Gregg W. Stone, Bruce R. Brodie, John J. Griffin, Marie Claude Morice, Costantino Costantini, Frederick G. St. Goar, Paul A. Overlie, Jeffrey J. Popma, JoAnn McDonnell, Denise Jones, William W. O’Neill, Cindy L. Grines, Prospective, multicenter study of the safety and feasibility of primary stenting in acute myocardial infarction : In-hospital and 30-day results of the PAMI stent pilot trial Journal of the American College of Cardiology. ,vol. 31, pp. 23- 30 ,(1998) , 10.1016/S0735-1097(97)00439-7
GRUPPOITALIANOPERLOSTUDIODELL, EFFECTIVENESS OF INTRAVENOUS THROMBOLYTIC TREATMENT IN ACUTE MYOCARDIAL INFARCTION The Lancet. ,vol. 327, pp. 397- 402 ,(1986) , 10.1016/S0140-6736(86)92368-8
Gregg W Stone, Dominic Marsalese, Bruce R Brodie, John J Griffin, Bryan Donohue, Costantino Costantini, Carlos Balestrini, Thomas Wharton, Paolo Esente, Michael Spain, Jeffrey Moses, Masakiyo Nobuyoshi, Mike Ayres, Denise Jones, Denise Mason, Lorelei Grines, William W O’Neill, Cindy L Grines, Second Primary Angioplasty in Myocardial Infarction (PAMI-II) Trial Investigators 1, A prospective, randomized evaluation of prophylactic intraaortic balloon counterpulsation in high risk patients with acute myocardial infarction treated with primary angioplasty Journal of the American College of Cardiology. ,vol. 29, pp. 1459- 1467 ,(1997) , 10.1016/S0735-1097(97)00088-0
Ali R. Moosvi, Fareed Khaja, Luis Villanueva, Mihai Gheorghiade, Lori Douthat, Sidney Goldstein, Early revascularization improves survival in cardiogenic shock complicating acute myocardial infarction Journal of the American College of Cardiology. ,vol. 19, pp. 907- 914 ,(1992) , 10.1016/0735-1097(92)90269-S
Jonathan Leor, Uri Goldbourt, Henrietta Reicher-Reiss, Elieser Kaplinsky, Solomon Behar, SPRINT Study Group, Cardiogenic shock complicating acute myocardial infarction in patients without heart failure on admission: Incidence, risk factors, and outcome The American Journal of Medicine. ,vol. 94, pp. 265- 273 ,(1993) , 10.1016/0002-9343(93)90058-W
Michael D. Hibbard, David R. Holmes, Kent R. Bailey, Guy S. Reeder, John F. Bresnahan, Bernard J. Gersh, Percutaneous transluminal coronary angioplasty in patients with cardiogenic shock. Journal of the American College of Cardiology. ,vol. 19, pp. 639- 646 ,(1992) , 10.1016/S0735-1097(10)80285-2