Identification of DeltaNp63alpha protein interactions by mass spectrometry.

作者: Angela Amoresano , Antonella Di Costanzo , Gabriella Leo , Ferdinando Di Cunto , Girolama La Mantia

DOI: 10.1021/PR9011156

关键词: Protein–protein interactionCell biologyIdentification (biology)Transcription factorPromoterMolecular biologyMass spectrometryChemistryLimb developmentGeneP53 Tumor Suppressor

摘要: p63, a transcription factor related to the p53 tumor suppressor, plays key role in epidermal differentiation and limb development. The gene has two distinct promoters that allow formation of ...

参考文章(24)
Cliff Tabin, Arlene Sharpe, Daniel Caput, Christopher Crum, Frank McKeon, Annie Yang, Ronen Schweitzer, Deqin Sun, Mourad Kaghad, Nancy Walker, Roderick T. Bronson, p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development Nature. ,vol. 398, pp. 714- 718 ,(1999) , 10.1038/19539
Guojun Wu, Shuji Nomoto, Mohammad Obaidul Hoque, Tatiana Dracheva, Motonabu Osada, Chyi Chia Richard Lee, Seung Myung Dong, Zhongmin Guo, Nicole Benoit, Yoram Cohen, Peggy Rechthand, Joseph Califano, Chul-so Moon, Edward Ratovitski, Jin Jen, David Sidransky, Barry Trink, None, ΔNp63α and TAp63α regulate transcription of genes with distinct biological functions in cancer and development Cancer Research. ,vol. 63, pp. 2351- 2357 ,(2003)
M. Levrero, V. De Laurenzi, A Costanzo, S Sabatini, J Gong, JYJ Wang, G Melino, The p53/p63/p73 family of transcription factors: overlapping and distinct functions Journal of Cell Science. ,vol. 113, pp. 1661- 1670 ,(2000) , 10.1242/JCS.113.10.1661
Antonella Di Costanzo, Luisa Festa, Olivier Duverger, Maria Vivo, Luisa Guerrini, Girolama La Mantia, Maria I. Morasso, Viola Calabrò, Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation. Cell Cycle. ,vol. 8, pp. 1185- 1195 ,(2009) , 10.4161/CC.8.8.8202
Alexey Fomenkov, Yi-Ping Huang, Ozlem Topaloglu, Anna Brechman, Motonobo Osada, Tanya Fomenkova, Eugene Yuriditsky, Barry Trink, David Sidransky, Edward Ratovitski, p63α Mutations Lead to Aberrant Splicing of Keratinocyte Growth Factor Receptor in the Hay-Wells Syndrome Journal of Biological Chemistry. ,vol. 278, pp. 23906- 23914 ,(2003) , 10.1074/JBC.M300746200
Jong Heon Kim, Bumsuk Hahm, Yoon Ki Kim, Mieyoung Choi, Sung Key Jang, Protein-protein interaction among hnRNPs shuttling between nucleus and cytoplasm Journal of Molecular Biology. ,vol. 298, pp. 395- 405 ,(2000) , 10.1006/JMBI.2000.3687
Seung‐Wook Chi, Ayeda Ayed, Cheryl H Arrowsmith, Solution structure of a conserved C‐terminal domain of p73 with structural homology to the SAM domain The EMBO Journal. ,vol. 18, pp. 4438- 4445 ,(1999) , 10.1093/EMBOJ/18.16.4438
Mariangela Rossi, Marco De Simone, Alessandra Pollice, Raffaela Santoro, Girolama La Mantia, Luisa Guerrini, Viola Calabrò, Itch/AIP4 Associates with and Promotes p63 Protein Degradation Cell Cycle. ,vol. 5, pp. 1816- 1822 ,(2006) , 10.4161/CC.5.16.2861
Abdeladim Moumen, Philip Masterson, Mark J. O'Connor, Stephen P. Jackson, hnRNP K: An HDM2 Target and Transcriptional Coactivator of p53 in Response to DNA Damage Cell. ,vol. 123, pp. 1065- 1078 ,(2005) , 10.1016/J.CELL.2005.09.032
Y. Fu, S. Wey, M. Wang, R. Ye, C.-P. Liao, P. Roy-Burman, A. S. Lee, Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 19444- 19449 ,(2008) , 10.1073/PNAS.0807691105