The future of stroke treatment.

摘要: The concept of the therapeutic window opportunity in ischemic neuronal injury and understanding necessity well organized stroke services revolutionized management acute during last years second millennium. Thrombolysis with IV rt-PA within 3 hours from onset symptoms is an established therapy for selected patients. challenge at outset this millennium how to translate basic pathophysiologic evidence into novel neuroprotective therapies either independently or combined thrombolysis. Great hopes are placed identification pivotal molecular events brain tissue design effective pharmacological interventions target them. Aggressive, invasive procedures also being developed such as intra-arterial clot lysis, hemicraniectomy mild hypothermia may improve bleakest outcomes associated most severe forms stroke, but their role must be rigorously evaluated. There is, however, no need wait future breakthroughs. existing strongly implies that good care patients starts organization entire chain; prehospital scene, through emergency room, unit. Without structured intervening likely outcome patient a stroke.