Mechanics of the lung in the 20th century.

摘要: Major advances in respiratory mechanics occurred primarily the latter half of 20th century, and this is when much our current understanding was secured. The earliest ancient investigations involving physiology were frequently done conjunction with other scientific activities often lacked ability to make quantitative measurements. This situation changed rapidly relatively recent history lung has been greatly influenced by critical technological applications, which have made experimental testing ideas possible. From spirometer Hutchinson, pneumotachograph Fleisch, measurement esophageal pressure, use Wilhelmy balance Clements, unassuming strain gauges for measuring pressure rapid paper electronic chart recorders, these enabling devices generated numerous studies increased physiologic validation mechanistic theories function health disease.