Association of nonmelanoma skin cancer and actinic keratosis with cumulative solar ultraviolet exposure in Maryland watermen

摘要: To establish the relationship between ultraviolet-B radiation and squamous cell carcinoma (SCC), basal (BCC), actinic keratosis (AK), a cross-sectional prevalence survey was performed in sample of 808 white, male watermen 30 years age older residing Eastern Shore Maryland. A measure personal cumulative exposure determined for each subject from data collected through interviews field laboratory measurements. interview elicited skin type, medication history, other factors. Clinical diagnoses histologic confirmation were done current previously removed tumors. The ratio subjects with SCC to BCC approximately 1:1; however, 1.25:1 because cases more prone multiple lesions. Watermen or AK but not had higher average annual doses than age-matched controls. This particularly marked younger 60 age. Logistic regression showed that an age, childhood freckling, blue eyes significantly increased risk development all three types tumor. Ease sunburning associated AK, SCC. upper quartile 2.5 times when compared lower 3 quartiles. suggests high levels are important occurrence. developing 1.5 those whose exceeded median. clear this different etiologic mechanisms operate BCC.