MiR-326: Promising Biomarker for Cancer.

作者: Yaojie Pan , Jian Wan , Chun-bin Wang

DOI: 10.2147/CMAR.S223875

关键词: Cell growthOncogeneCancer researchMetastasisBiologyCancermicroRNABiomarkerCarcinogenesisSignal transduction

摘要: MicroRNAs (miRNAs) are small non-coding and highly conserved RNAs that act in biological processes including cell proliferation, invasion, apoptosis, metabolism, signal transduction, tumorigenesis. The previously identified miRNA-326 (miR-326) has been reported to participate cellular tumor growth, embryonic development, immunomodulation, chemotherapy resistance, oncogenesis. This review presents a detailed overview of what is known about the effects miR-326 on metastasis, drug its involvement signaling pathways.

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