Expanding the threonine aldolase toolbox for the asymmetric synthesis of tertiary α-amino acids.

作者: Kateryna Fesko , Gernot A. Strohmeier , Rolf Breinbauer

DOI: 10.1007/S00253-015-6803-Y

关键词: BiochemistrySerineStereochemistryEnzyme catalysisAmino acidThreonineEnantioselective synthesisAlanineBiologyEnzymeThreonine aldolase

摘要: … The new enantiocomplementary l- and d-threonine aldolases catalyze the asymmetric synthesis of β-hydroxy α-methyl- and α-hydroxymethyl-α-amino acids with good conversion and …

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