Biophotonic logic devices based on quantum dots and temporally-staggered Förster energy transfer relays

摘要: Integrating photonic inputs/outputs into unimolecular logic devices can provide significantly increased functional complexity and the ability to expand repertoire of available operations. Here, we build upon a system previously utilized for biosensing assemble prototype several increasingly sophisticated biophotonic that function based multistep Forster resonance energy transfer (FRET) relays. The core combines central semiconductor quantum dot (QD) nanoplatform with long-lifetime Tb complex FRET donor near-IR organic fluorophore acceptor; latter acts as two unique inputs QD-based device. allows form temporal memory by providing access time-delayed modality an alternate output which increases inherent computing options. Altering device controlling configuration parameters biologically self-assembly provides input control while monitoring changes in emission all participants, both spectral temporal-dependent manner, gives rise input, single Boolean Logic operations including OR, AND, INHIBIT, XOR, NOR, NAND, along possibility gate transitions. Incorporation enzymatic cleavage step set-reset be implemented repeatedly same building blocks is demonstrated YES NOT gates. Potential applications these are discussed context their constituent parts richness signal.