Alterations in γ-aminobutyric acid content in the rat superior cervical ganglion and pineal gland
作者： Robert A. Waniewski , Amin Suria
DOI: 10.1016/0024-3205(77)90112-6
关键词: Endocrinology 、 Microwave irradiation 、 Internal medicine 、 Rat Pineal Gland 、 Functional role 、 Pineal gland 、 Endogeny 、 Aminobutyric acid 、 Biology 、 Superior cervical ganglion 、 General Pharmacology, Toxicology and Pharmaceutics 、 General Biochemistry, Genetics and Molecular Biology 、 General Medicine
摘要: Abstract The endogenous γ-aminobutyric acid (GABA) content of the rat pineal gland and superior cervical ganglion (SCG) was measured by high pressure liquid chromatography. It found that GABA levels in both tissues increased after decapitation animals. frozen within 20 seconds same as removed from animals killed microwave irradiation. Amino-oxyacetic acid, a GABA-transaminase inhibitor, these tissues. Dimethylphenylpiperizinium or isoniazid administration did not alter Isoproterenol SCG but change levels. ability to take up accumulate 3 H-GABA significantly reduced rats had been ganglionectomized. A fluctuation seen occur when measures were taken at different times day. These results tend suggest may have some functional role ganglion.
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