Vertebral body corner oedema vs gadolinium enhancement as biomarkers of active spinal inflammation in ankylosing spondylitis
作者： YX J Wang , J F Griffith , M Deng , TK Li , LS Tam
DOI: 10.1259/BJR/29661937
关键词: Meglumine 、 Intraclass correlation 、 Myelitis 、 Infliximab 、 Radiology 、 Magnetic resonance imaging 、 Whole body imaging 、 Lesion 、 Medicine 、 Ankylosing spondylitis
摘要: Objective To investigate the relative performance of T2 weighted short tau inversion–recovery (STIR) and fat-suppressed T1 gadolinium contrast-enhanced sequences in depicting active inflammatory lesions ankylosing spondylitis (AS). Methods Whole-spine MRI was performed on 32 patients with AS, who participated a clinical trial infliximab treatment, by STIR at baseline after 30 weeks. The AS spine MRI-activity (ASspiMRI-a) scoring method used. images from these two imaging techniques were evaluated separately independent readers. Results For pre-treatment lesion status, intraclass correlation coefficients comparing readings 0.69±0.23 for Reader 1 0.65±0.21 2. At baseline, mean ASspiMRI-a score 15.4% 17.7% higher than 2, respectively. After rated an r...
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