The microencapsulated ascorbic acid release in vitro and its effect on iron bioavailability.

作者: Jun-Beum Lee , Joungjwa Ahn , Jonghwi Lee , Hae-Soo Kwak

DOI: 10.1007/BF02980035

关键词: Coating materialsIn vitroSerum ironFerricAscorbic acidInorganic chemistryAmmonium sulfateIncubationChemistryBioavailabilityChromatography

摘要: The present study was carried out to examine the stability of microencapsulated ascorbic acid in simulated-gastric and intestinal situationin vitro effect on iron bioavailability. Coating materials used were polyglycerol monostearate (PGMS) medium-chain triacylglycerol (MCT), core L-ascorbic ferric ammonium sulfate. When by MCT, release 6.3% at pH 5 1.32% 2 fluids during 60 min. PGMS, more released range 9.5 16.0%. Comparatively, increased significantly as 94.7% 83.8% coated MCT respectively, for min incubation simulated-intestinal fluid. In subsequent study, we tested whether enhanced bioavailability or not. results, serum content transferring saturation dramatically when subjects consumed milks containing both encapsulated acid, compared with those uncapsulated without acid. Therefore, data indicated that PGMS effective means fortifying into milk enhancing

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