The Copper Chelator d-Penicillamine Delays Onset of Disease and Extends Survival in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis
作者： Andreas F. Hottinger , Eric G. Fine , Mark E. Gurney , Anne D. Zurn , Patrick Aebischer
DOI: 10.1111/J.1460-9568.1997.TB01511.X
关键词: Immunology 、 Amyotrophic lateral sclerosis 、 Genetically modified mouse 、 Mutant 、 In vivo 、 Endocrinology 、 Penicillamine 、 Mutation 、 Internal medicine 、 Superoxide dismutase 、 SOD1 、 Biology
摘要: … by copper chelators. To test this hypothesis in vivo, we administered the copper chelator d-… These results suggest that copper chelators may benefit patients with familial amyotrophic …
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