Randomized Controlled Trial of Mindfulness-Based Cancer Recovery Versus Supportive Expressive Group Therapy for Distressed Survivors of Breast Cancer (MINDSET)

作者: Linda E. Carlson , Richard Doll , Joanne Stephen , Peter Faris , Rie Tamagawa

DOI: 10.1200/JCO.2012.47.5210

关键词: Social supportPsychological interventionRandomized controlled trialMoodMedicinePhysical therapyGroup psychotherapyMindfulnessStress managementBreast cancer

摘要: Purpose To compare the efficacy of following two empirically supported group interventions to help distressed survivors breast cancer cope: mindfulness-based recovery (MBCR) and supportive-expressive therapy (SET). Patients Methods This multisite, randomized controlled trial assigned 271 stage I III MBCR, SET, or a 1-day stress management control condition. MBCR focused on training in mindfulness meditation gentle yoga, whereas SET emotional expression support. Both intervention groups included 18 hours professional contact. Measures were collected at baseline after by assessors blind study Primary outcome measures mood diurnal salivary cortisol slopes. Secondary outcomes symptoms, quality life, social Results Using linear mixed-effects models, intent-to-treat analyses, slopes maintained over time both (P = .002) MBC...

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