Critical Review of the Alzheimer's Disease Non-Transgenic Models: Can They Contribute to Disease Treatment?
作者： Julio A. Flores-Cuadra , Alanna Madrid , Patricia L. Fernández , Ambar R. Pérez-Lao , Diana C. Oviedo
DOI: 10.3233/JAD-200870
关键词: Bioinformatics 、 Transgene 、 Drug discovery 、 Medicine 、 Intervention (counseling) 、 Pathological 、 Dementia 、 Disease treatment 、 Disease 、 Amyloid
摘要: Alzheimer’s disease (AD) is a growing neurodegenerative disease without effective treatments or therapies. Despite the use of different approaches and an extensive variety of genetic …
sci-hub.st 参考文章(278)
Gunjan Saxena, Sheelendra Pratap Singh, Rahul Agrawal, Chandishwar Nath, Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice European Journal of Pharmacology. ,vol. 581, pp. 283- 289 ,(2008) , 10.1016/J.EJPHAR.2007.12.009
Annaliese K. Beery, Irving Zucker, Sex bias in neuroscience and biomedical research Neuroscience & Biobehavioral Reviews. ,vol. 35, pp. 565- 572 ,(2011) , 10.1016/J.NEUBIOREV.2010.07.002
Shanshan Zhou, Guichun Yu, Lijun Chi, Jiwei Zhu, Wei Zhang, Yan Zhang, Liming Zhang, Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats. Neurotoxicology. ,vol. 38, pp. 136- 145 ,(2013) , 10.1016/J.NEURO.2013.07.007
Peng Liu, Libo Zou, Qing Jiao, Tianyan Chi, Xuefei Ji, Yue Qi, Qian Xu, Lihua Wang, Xanthoceraside attenuates learning and memory deficits via improving insulin signaling in STZ-induced AD rats Neuroscience Letters. ,vol. 543, pp. 115- 120 ,(2013) , 10.1016/J.NEULET.2013.02.065
Paweł Grieb, Intracerebroventricular Streptozotocin Injections as a Model of Alzheimer’s Disease: in Search of a Relevant Mechanism Molecular Neurobiology. ,vol. 53, pp. 1741- 1752 ,(2016) , 10.1007/S12035-015-9132-3
Anand Kamal Sachdeva, Shubham Misra, Indu Pal Kaur, Kanwaljit Chopra, Neuroprotective potential of sesamol and its loaded solid lipid nanoparticles in ICV-STZ-induced cognitive deficits: behavioral and biochemical evidence. European Journal of Pharmacology. ,vol. 747, pp. 132- 140 ,(2015) , 10.1016/J.EJPHAR.2014.11.014
Anand Kamal Sachdeva, Anurag Kuhad, Kanwaljit Chopra, Naringin ameliorates memory deficits in experimental paradigm of Alzheimer's disease by attenuating mitochondrial dysfunction. Pharmacology, Biochemistry and Behavior. ,vol. 127, pp. 101- 110 ,(2014) , 10.1016/J.PBB.2014.11.002
Shizuo Nakamura, Norihito Murayama, Takafumi Noshita, Hirokazu Annoura, Tomochika Ohno, Progressive brain dysfunction following intracerebroventricular infusion of beta1–42-amyloid peptide Brain Research. ,vol. 912, pp. 128- 136 ,(2001) , 10.1016/S0006-8993(01)02704-4
G Grazia, C Vegetti, F Benigni, I Penna, V Perotti, E Tassi, I Bersani, G Nicolini, S Canevari, C Carlo-Stella, A M Gianni, R Mortarini, A Anichini, Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma. Cell Death and Disease. ,vol. 5, pp. 1- 12 ,(2014) , 10.1038/CDDIS.2014.410
Yongchang Diwu, Jinzhou Tian, Jing Shi, Effect of Xixin decoction on phosphorylation toxicity at specific sites of tau protein in brains of rats with sporadic Alzheimer disease Journal of Traditional Chinese Medicine. ,vol. 33, pp. 787- 793 ,(2013) , 10.1016/S0254-6272(14)60013-3