Intestinal inflammation and cancer

作者: Thomas A. Ullman , Steven H. Itzkowitz

DOI: 10.1053/J.GASTRO.2011.01.057

关键词: CancerColorectal cancerColitisInflammatory bowel diseaseUlcerative colitisMouse model of colorectal and intestinal cancerBiologyPrimary sclerosing cholangitisCarcinogenesisImmunology

摘要: … Patients with the inflammatory bowel diseases (IBD) ulcerative colitis (UC) or Crohn's colitis … cancer (CRC). This increase in risk is more likely to result from chronic inflammation of the …

参考文章(87)
Amy Noffsinger, Susan Kretschmer, Jenine Belli, Franz Fogt, Cecilia Fenoglio-Preiser, Microsatellite instability is uncommon in intestinal mucosa of patients with Crohn's disease. Digestive Diseases and Sciences. ,vol. 45, pp. 378- 384 ,(2000) , 10.1023/A:1005433231058
Glenna C. Burmer, Peter S. Rabinovitch, Rodger C. Haggitt, David A. Crispin, Teresa A. Brentnall, Venkateswara R. Kolli, Allyn C. Stevens, Cyrus E. Rubin, Neoplastic progression in ulcerative colitis: Histology, DNA content, and loss of a p53 allele Gastroenterology. ,vol. 103, pp. 1602- 1610 ,(1992) , 10.1016/0016-5085(92)91184-6
Stephen J. Meltzer, Fumiaki Sato, Kena Desai, Anatoly Leytin, Jing Yin, Suna Wang, Yuriko Mori, Florin M. Selaru, John M. Abraham, Noam Harpaz, David Shibata, Yan Xu, Tong-Tong Zou, Hypermethylation of the p14ARF Gene in Ulcerative Colitis-associated Colorectal Carcinogenesis Cancer Research. ,vol. 62, pp. 1148- 1151 ,(2002)
Jonathan S. Stamler, Fanny Karmeli, Mark E. Mullins, David J. Singel, Joseph Loscalzo, Ramnik J. Xavier, Daniel K. Podolsky, Daniel Rachmilewitz, Peroxynitrite-induced rat colitis--a new model of colonic inflammation. Gastroenterology. ,vol. 105, pp. 1681- 1688 ,(1993) , 10.1016/0016-5085(93)91063-N
Masami Morotomi, Shoichi Kado, Yoshiaki Matsuoka, Yuriko Nagata, Kazumi Uchida, Masaharu Onoue, Shin Iwata, Makoto Ohwaki, Hideyuki Funabashi, Minoru Ando, Intestinal Microflora Are Necessary for Development of Spontaneous Adenocarcinoma of the Large Intestine in T-Cell Receptor β Chain and p53 Double-Knockout Mice Cancer Research. ,vol. 61, pp. 2395- 2398 ,(2001)
Jing Yin, Noam Harpaz, Yi Tong, Ying Huang, Jacqueline Laurin, Bruce D. Greenwald, Maria Hontanosas, Carnell Newkirk, Stephen J. Meltzer, p53 Point mutations in dysplastic and cancerous ulcerative colitis lesions Gastroenterology. ,vol. 104, pp. 1633- 1639 ,(1993) , 10.1016/0016-5085(93)90639-T
Maija R. J. Kohonen-Corish, Jane E. Dahlstrom, Joseph J. Daniel, Hein te Riele, Gary D. Buffinton, Susceptibility of Msh2-deficient Mice to Inflammation-associated Colorectal Tumors Cancer Research. ,vol. 62, pp. 2092- 2097 ,(2002)
A. Steven Fleisher, Stephen J. Meltzer, Manel Esteller, O. Colin Stine, Anatoly Leytin, Stephen P. James, Jing Yin, Keith T. Wilson, John M. Abraham, Dehe Kong, Jing Liang, James G. Herman, Noam Harpaz, Yan Xu, Asma Rashid, Tong-Tong Zou, Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Research. ,vol. 60, pp. 4864- 4868 ,(2000)
Dan Pinczowski, Anders Ekbom, John Baron, Jonathan Yuen, Hans-Olov Adami, Risk factors for colorectal cancer in patients with ulcerative colitis: A case-control study Gastroenterology. ,vol. 107, pp. 117- 120 ,(1994) , 10.1016/0016-5085(94)90068-X
Cyrus E. Rubin, Rodger C. Haggitt, Glenna C. Burmer, Teresa A. Brentnall, Allyn C. Stevens, Douglas S. Levine, Patrick J. Dean, Michael Kimmey, David R. Perera, Peter S. Rabinovitch, DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis. Gastroenterology. ,vol. 103, pp. 1611- 1620 ,(1992) , 10.1016/0016-5085(92)91185-7