Results of Surgical Treatment for Infective Endocarditis in Intravenous Drug Users

摘要: Objective: To determine the early and late results of surgical treatment for infective endocarditis (IE) in intravenous drug users (IVDU). Design: Cohort study consecutive IVDUs undergoing IE. Setting: Large public hospital serving urban population Chicago, Ill. Patients: Consecutive operated on between July 1982 June 1991 Main outcome measures: Death, stroke, noncerebral systemic embolization, major bleeding, recurrent endocarditis, repeated valve replacement. Results: There were 80 patients, 58 men 22 women, with a mean age 37.5 ± 10 (SD) years. The course all patients follow-up data 75 (94%) complete. primary indication surgery was acute congestive heart failure 44 (56%), persistent sepsis 21 (26%), multiple embolization 15 (19%) patients. Six (7.5%) died within 30 days surgery. An additional 13 69 (17.6%) during follow-up, 8 from cardiovascular causes. probability survival at 36 months 60 0.74 0.05 (SE) 0.70 0.05, respectively. Seventeen (30%) survivors had least one event; 6 (8.8%) 4 (5.8%) 3 (4.4%) extracerebral 1 embolism, required Probability event-free 0.65 0.06 0.52 0.08, median duration 65 months. Conclusion: Since expected mortality without IE whom medical fails is almost 100%, it concluded that indicated for, substantially improves outlook of, who fail to respond management.