Nongenetic control of receptor signaling dynamics using a DNA-based optochemical tool.
作者： Shinsuke Sando , Yasuteru Urano , Tasuku Ueno , Ryosuke Ueki , Shota Hayashi
DOI: 10.1039/D1CC01968F
关键词: Cellular functions 、 A-DNA 、 Growth factor 、 Target protein 、 Computational biology 、 Biology 、 Receptor signaling
摘要: Optochemical tools that can modulate activity of the target protein provide an opportunity for studying and regulating related biological processes. Here we present a DNA-based nongenetic optochemical tool control dynamics growth factor signaling. This photo-caged mimicry be promising elucidating linkage between signaling resulting outcomes, as well manipulating cellular functions fate living cells.
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