Methods for preventing acute clinical vascular events in a subject

摘要: This invention provides methods for: (i) inhibiting macrophage death, (ii) atherosclerotic lesional complications, and (iii) necrosis, plaque rupture and/or superficial erosion, in a subject having, or at increased risk for developing, cardiovascular disease which comprise administering to the an effective amount of amphiphilic compound pharmaceutically acceptable salt thereof inhibits intracellular transport cholesterol within cells free cholesterol-induced death cells, wherein is from storage site endoplasmic reticulum. also articles manufacture comprising reticulum use disease.