Rapid access to unsymmetrical 1,3-diynes and 2,5-disubstituted thiophenes under ligand and Pd/Ni-free Cu-catalysis
作者： Maddali L. N. Rao , Sk Shamim Islam , Priyabrata Dasgupta
DOI: 10.1039/C5RA15705F
关键词: Combinatorial chemistry 、 Chemistry 、 Stereochemistry 、 Ligand 、 Catalysis 、 Rapid access 、 Tandem
摘要: A Pd/Ni-free copper-catalysed tandem synthesis was realized for rapid access to unsymmetrical 1,3-diynes from 1,1-dibromoalkenes and terminal alkynes. This method extended the straightforward of 2,5-disubstituted thiophenes in a one-pot operation.
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