Macrophage Detection in Aortic Aneurysm

作者: Robin P. Choudhury

DOI: 10.1161/ATVBAHA.111.223297

关键词: Aortic aneurysmFunctional imagingAneurysmSudden deathProteolytic enzymesRadiologyPathologicalPredictive value of testsMacrophageMedicineCardiology and Cardiovascular Medicine

摘要: Aortic aneurysm is a common condition that associated with risk of rupture and sudden death. Clinical screening surveillance are based largely on noninvasive assessment diameter rate change diameter, often serial ultrasound examination. An ability to identify vessel characteristics or processes enlargement predictive would be valuable in guiding the selection patients for repair optimizing timing intervention. Current approaches, focused detection these anatomic changes, reflect relatively late stage pathology, which dilatation structural changes have already occurred. Overlooked gross imaging pathological relating enlargement, including cellular infiltration1 secretion proteolytic enzymes degrade components arterial wall.2,3 See accompanying article page 750 To focus critical will require development molecular, cellular, functional techniques potential accelerate refine diagnosis, determine prognosis, guide …

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