Superparamagnetic nanoparticles as a contrast agent for magnetic resonance imaging (mri) of magnetic susceptibility (t2

作者: Egea Fernando Moreno , Hernández Daniel Calle , Garcia-Esteller Sebastián Cerdan

DOI:

关键词: Magnetic resonance imagingCoatingTissue imagingAdhesionMagnetic susceptibilitySuperparamagnetic nanoparticlesNanoparticleNuclear magnetic resonanceMaterials scienceIn vivo

摘要: The invention relates to the use of biocompatible superparamagnetic nanoparticles comprising an inorganic core and a coating including electrically charged polymer, having low tissue vascular adhesion, for as contrast agents in magnetic resonance imaging (MRI). aforementioned have novel pharmacokinetic relaxability T2* properties, with high potential vivo tumour perfusion strategies based on parameter T2*.

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