Retinoid-modulated MAT1 ubiquitination and CAK activity

作者: Qiaojun He , Hui Peng , Steven J. Collins , Timothy J. Triche , Lingtao Wu

DOI: 10.1096/FJ.04-2182FJE

关键词: Cyclin-dependent kinase 3Cyclin-dependent kinase 9Cell biologyCyclin-dependent kinase 2Cyclin-dependent kinase 4BiochemistryCyclin-dependent kinase 7Cyclin-dependent kinaseCyclin-dependent kinase 1Mitogen-activated protein kinase kinaseChemistry

摘要: SPECIFIC AIMSHuman cyclin-dependent kinase (CDK)-activating (CAK) consists of CDK7, cyclin H, and MAT1 (menage a trois 1). CAK cross-regulates cell cycle differentiation whereas ass...

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