Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii

作者: Milad Iranshahy , Hamideh Javidi-Shirazi , Ngoc B. Pham , Ronald J. Quinn , Hamid Sadeghian

DOI: 10.1080/10286020.2014.969717

关键词: Two-dimensional nuclear magnetic resonance spectroscopyAlamar blueAdlumiceine methyl esterIC50AlkaloidOrganic chemistryFumariaPapaveraceaeStereochemistryFumaria vaillantiiChemistry

摘要: A new alkaloid, adlumiceine methyl ester (1), together with two known alkaloids, parfumine (2) and N-methylhydrastine (3), was isolated from aerial parts of Fumaria vaillantii. The structures compounds were determined by 1D/2D NMR MS data. All three tested for cytotoxic activity against PC3 MCF7 cell lines using Alamar blue assay. showed no significant (IC50>50 μM) lines.

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