Consequences of Chronic Sleep Restriction on Energy Balance in Healthy Adults

摘要: Habitual short sleep duration is consistently associated with weight gain and increased risk for obesity. The objective of this dissertation was to elucidate how chronic restriction impacts components energy balance, namely, gain, intake, expenditure. Healthy adults (21-50 y) participated in controlled isolated laboratory protocols 14-18 days were randomized either an experimental condition (baseline followed by [5 consecutive nights 4 hours time-in-bed [TIB] per night] recovery sleep) or control (no restriction: 10 TIB night all nights). Sleep-restricted subjects exhibited significant caloric greater consumption fat, delayed meal timing decreased resting metabolic rate (the largest component expenditure) during but these changes returned baseline levels after one (12 TIB). Control did not exhibit a change weight, intake across corresponding protocol days. Notably, there gender race differences the balance response restriction. Men gained more degree consumed larger percentage calories late-night than women. Relative Caucasians, African Americans comparable amount marked expenditure deficits sleep, study. In largest, most diverse healthy sample studied date under conditions, promoted positive balance. Collectively, results highlight importance obtaining sufficient regulating maintaining particularly men Americans. Degree Type Dissertation Name Doctor Philosophy (PhD) Graduate Group Psychology First Advisor David F. Dinges