作者: Talita Gnoato Zotz , Luiz Guilherme A. Capriglione , Rafael Zotz , Lucia Noronha , Marina Louise Viola De Azevedo
DOI: 10.1016/J.ACTHIS.2015.10.004
关键词: Medicine 、 Physical therapy 、 Endocrinology 、 Sarcomere 、 Type I collagen 、 Sarcopenia 、 Soleus muscle 、 Internal medicine 、 Skeletal muscle 、 Static stretching 、 Sarcomerogenesis 、 Flexibility (anatomy)
摘要: Abstract It has been shown that stretching exercises can improve the flexibility and independence of elderly. However, although these commonly constitute training programs, morphological adaptations induced by in aged skeletal muscle are still unclear. Objective To assess acute effects passive mechanical static on morphology, sarcomerogenesis modulation important components extracellular matrix soleus female rats. Methods Fifteen old rats with 26 months were divided into two groups: ( n = 8, SG) control = 7, CG): The protocol consisted 4 repetitions each 1 min 30 s interval between sets. Stretching was performed left muscle, 3 times a week for 1 week. After three sessions, anesthetized to remove then euthanized. following analyses carried out: fiber cross-sectional area serial sarcomere number; immunohistochemistry quantification collagen I, III TGFβ-1. Results decrease SG observed when compared CG p = 0.0001, Kruskal–Wallis); percentage type I significantly lower = 0.01, Kruskal–Wallis), as well TGFβ-1 = 0.04, higher than (7.06 ± 6.88% vs 4.92 ± 5.30%, Kruskal–Wallis). Conclusion Although hypotrophy, an antifibrotic action detected.