Biodiversity, the Human Microbiome and Mental Health: Moving toward a New Clinical Ecology for the 21st Century?

摘要: Advances in research concerning the brain-related influences of microbiome have been paradigm shifting, although at an early stage, clinical involving beneficial microbes lends credence to notion that may be important target supporting mental health (defined here along continuum between quality life and criteria for specific disorders). Through metagenomics, proteomics, metabolomics, systems biology, a new emphasis personalized medicine is on horizon. Humans can now viewed as multispecies organisms operating within ecological theatre; it clinicians increasingly see their patients this context. Historically marginalized aspects are destined become consideration frontiers practicing with mind. Emerging evidence indicates macrobiodiversity external environment influence well-being. Local biodiversity also drive differences human-associated microbiota; microbial diversity product far-reaching effects immune function mood. With focus pertains health, we define environmental “grey space” emphasize frontier bio-eco-psychological medicine. Within concept terrain link dysbiotic lifestyles grand scale local ecosystems might otherwise seem far removed from one another.